Transform Cancer Cells Back to Normal

Scientists have created technology to transform cancer cells back to normal.

While most cancer treatments aim to destroy cancer cells, this approach often leads to issues like drug resistance, recurrence, and damage to healthy cells.

Researchers at KAIST, led by Professor Kwang-Hyun Cho from the Department of Bio and Brain Engineering, have developed an innovative method to treat colon cancer without killing cancer cells. Instead, the technology reprograms cancer cells to resemble normal colon cells, reducing harmful side effects.

The team discovered that cancer cells regress along their differentiation pathway during tumor formation. Using this insight, they created a “digital twin” of the gene network involved in cell differentiation, paving the way for a new direction in cancer therapy.

source KAIST